Publications

• The open to closed D-loop conformational switch determines length in filopodia-like actin bundles.Gadsby JR, Savvas Ioannou P, Butler R, Mason J, Smith A, Dobramysl U, Chin S, Dobson C, Gallop JL. https://doi.org/10.1101/2024.08.09.607305 [bioRxiv]
• Filopodial protrusion driven by density-dependent Ena-TOCA-1 interactions. Blake TCA, Fox HM, Urbančič V, Ravishankar R, Wolowczyk A, Allgeyer ES, Mason J, Danuser G, Gallop JL. J Cell Sci. 2024 Mar 15;137(6):jcs261057. doi: 10.1242/jcs.261057 [full text] [PMC]
• Filopodia in vitro and in vivo. Blake TCA and Gallop JL. Annu. Rev. Cell Dev. Biol. (2023) 39, 307-329. 10.1146/annurev-cellbio-020223-025210 [full text]
• Stochastic combinations of actin regulatory proteins are sufficient to drive filopodia formation. Dobramysl U, Jarsch IK, Inoue I, Shimo H, Richier B, Gadsby JR, Mason J, Szalapak A, Ioannou P, Correia Pereira G, Walrant A, Butler R, Hannezo E, Simons BD, Gallop JL. J Cell Biol (2021) 220 (4): e202003052 [full text] [PMC]
• The phosphoinositide 3-kinase inhibitor alpelisib restores actin organization and improves proximal tubule dysfunction in vitro and in a mouse model of Lowe syndrome and Dent disease. Berquez M, Gadsby JR, Festa BP, Butler R, Jackson SP, Verno V, Luciani A, Devuyst O, Gallop JL. Kidney Int (2020) 98(4):883-896 [PMC]
• A direct role for SNX9 in the biogenesis of filopodia. Jarsch IK, Gadsby JR, Nuccitelli A, Mason J, Shimo H, Pilloux L, Marzook B, Mulvey CM, Dobramysl U, Lilley KS, Hayward RD, Vaughan TJ, Dobson CL, Gallop JL. J Cell Biol (2020) 219 (4): e201909178. [full text] [PMC]
• Filopodia and their links with membrane traffic and cell adhesion. Gallop JL. Semin Cell Dev Biol. 2019 Dec 13. pii: S1084-9521(18)30333-1. [full text] [pubmed]
• Filopodia-Like Structure Formation from Xenopus Egg Extracts. Fox HM and Gallop JL. Cold Spring Harb Protoc. 2019 Feb 1;2019(2) doi: 10.1101/pdb.prot100545 [full text]
• Integrin signaling downregulates filopodia in muscle-tendon attachment. Richier B, Inoue Y, Dobramysl U, Friedlander J, Brown NH, Gallop JL. J Cell Sci 2018; 131:jcs217133. [full text] [PMC]
• Control of actin polymerization via the coincidence of phosphoinositides and high membrane curvature. Daste F, Walrant A, Holst MR, Gadsby JR, Mason J, Lee JE, Brook D, Mettlen M, Larsson E, Lee SF, Lundmark R, Gallop JL. J Cell Biol. 2017. doi: 10.1083/jcb.201704061. [full text][PMC]
• Filopodyan: An open-source pipeline for the analysis of filopodia. Urbančič V, Butler R, Richier B, Peter M., Mason J, Livesey FJ, Holt CE, and Gallop JL. J Cell Biol. 2017; 216:3405–3422. [full text][PMC] [GitHub]
• Membrane curvature in cell biology: An integration of molecular mechanisms. Jarsch IK, Daste F, and Gallop JL. J Cell Biol. 2016; 216 (4): 375-387. [full text][PMC]
• Investigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES. Watson JR, Fox HM, Nietlispach D, Gallop JL, Owen D, Mott HR J Biol Chem. 2016; 291(26):13875-90. [full text][PMC]
• Triggering actin polymerization in Xenopus egg extracts from phosphoinositide-containing lipid bilayers. Walrant A, Saxton DS, Correia Pereira G, Gallop JL. Methods in Cell Biology. 2015; 128:125-47. [full text][pubmed]
• Phosphoinositides and membrane curvature switch the mode of actin polymerization via selective recruitment of toca-1 and Snx9. Gallop JL, Walrant A, Cantley LC, Kirschner MW. Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7193-8. [full text][PMC]
• Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration. Love NR, Chen Y, Ishibashi S, Kritsiligkou P, Lea R, Koh Y, Gallop JL, Dorey K, Amaya E. Nat Cell Biol. 2012 Dec 23;15(2):222-8. [full text][PMC]
• Self-assembly of filopodia-like structures on supported lipid bilayers. Lee K, Gallop JL, Rambani K, Kirschner MW. Science. 2010 Sep 10;329(5997):1341-5. [full text][PMC]

           From Jenny’s previous work on                                membrane curvature

• Membrane binding and self-association of the epsin N-terminal homology domain. Lai CL, Jao CC, Lyman E, Gallop JL, Peter BJ, McMahon HT, Langen R, Voth GA. J Mol Biol. 2012 Nov 9;423(5):800-17. [full text][PMC]
• Endophilin drives the fast mode of vesicle retrieval in a ribbon synapse. Llobet A, Gallop JL, Burden JJ, Camdere G, Chandra P, Vallis Y, Hopkins CR, Lagnado L, McMahon HT. J Neurosci. 2011 Jun 8;31(23):8512-9. [full text][PMC]
• Roles of amphipathic helices and the bin/amphiphysin/rvs (BAR) domain of endophilin in membrane curvature generation. Jao CC, Hegde BG, Gallop JL, Hegde PB, McMahon HT, Haworth IS, Langen R. J Biol Chem. 2010 Jun 25;285(26):20164-70 [full text][PMC]
• Mechanism of endophilin N-BAR domain-mediated membrane curvature. Gallop JL, Jao CC, Kent HM, Butler PJ, Evans PR, Langen R, McMahon HT. EMBO J. 2006 Jun 21;25(12):2898-910. [full text][PMC]
• Endophilin and CtBP/BARS are not acyl transferases in endocytosis or Golgi fission. Gallop JL, Butler PJ, McMahon HT. Nature. 2005 Dec 1;438(7068):675-8. [full text][PMC]
• Membrane curvature and mechanisms of dynamic cell membrane remodelling. McMahon HT, Gallop JL. Nature. 2005 Dec 1;438(7068):590-6. Review. [full text][pubmed]
• BAR domains and membrane curvature: bringing your curves to the BAR. Gallop JL, McMahon HT. Biochem Soc Symp. 2005;(72):223-31. Review. [pubmed]
• Evolving nature of the AP2 alpha-appendage hub during clathrin-coated vesicle endocytosis. Praefcke GJ, Ford MG, Schmid EM, Olesen LE, Gallop JL, Peak-Chew SY, Vallis Y, Babu MM, Mills IG, McMahon HT. EMBO J. 2004 Nov 10;23(22):4371-83. [full text][PMC]
• EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking. Mills IG, Praefcke GJ, Vallis Y, Peter BJ, Olesen LE, Gallop JL, Butler PJ, Evans PR, McMahon HT. J Cell Biol. 2003 Jan 20;160(2):213-22. [full text][PMC]